Inspecting fairly thoroughly for signs of bed bugs when you first arrive in a room can be very helpful. Include checking the bedding (especially near any attached type of bed headboard), the luggage holding rack, night stands by any bed (remember to check underneath and inside drawers if possible), closet shelves, dresser drawers, and along carpet edges under and near (e.g., within about 5 feet of) any bed. Report any evidence of bed bugs to the management immediately for their corrective actions. Just moving to a different room may not be the total answer. You should repeat the thorough inspection of any new or different room you are offered. When you pack to leave, inspect your luggage carefully first, and inspect every item as you pack to help detect any bugs or their signs. Laundering most cloth items with typical hot water and detergent followed by drying on low heat for at least 20 minutes (or standard dry cleaning) should kill all bed bugs in or on such items. Sealing freshly-laundered items inside a plastic bag should help keep any more bed bugs from getting in those items later to hide (and be carried back with you). Initially detecting and then excluding the bugs is the usually best strategy.
Courtesy of:Harold Harlan, who was a career bug expert for the military, is a prominent authority on bed bugs